Detalhe da pesquisa
1.
Pliability in the m6A-Binding Region Extends Druggability of YTH Domains.
J Chem Inf Model
; 64(5): 1682-1690, 2024 Mar 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-38417111
2.
Novel Pyrimidine Derivatives as Antioxidant and Anticancer Agents: Design, Synthesis and Molecular Modeling Studies.
Molecules
; 28(9)2023 May 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-37175322
3.
Discovery and antiviral profile of new sulfamoylbenzamide derivatives as HBV capsid assembly modulators.
Bioorg Med Chem Lett
; 73: 128904, 2022 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35868496
4.
Machine Learning Analyses on Data including Essential Oil Chemical Composition and In Vitro Experimental Antibiofilm Activities against Staphylococcus Species.
Molecules
; 24(5)2019 Mar 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-30832446
5.
Disruptor of telomeric silencing 1-like (DOT1L): disclosing a new class of non-nucleoside inhibitors by means of ligand-based and structure-based approaches.
J Comput Aided Mol Des
; 32(3): 435-458, 2018 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-29335872
6.
Antimicrobial and Antibiofilm Activity and Machine Learning Classification Analysis of Essential Oils from Different Mediterranean Plants against Pseudomonas aeruginosa.
Molecules
; 23(2)2018 Feb 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-29473844
7.
Understanding the Molecular Determinant of Reversible Human Monoamine Oxidase B Inhibitors Containing 2H-Chromen-2-One Core: Structure-Based and Ligand-Based Derived Three-Dimensional Quantitative Structure-Activity Relationships Predictive Models.
J Chem Inf Model
; 57(4): 787-814, 2017 04 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-28291352
8.
Exploring the first Rimonabant analog-opioid peptide hybrid compound, as bivalent ligand for CB1 and opioid receptors.
J Enzyme Inhib Med Chem
; 32(1): 444-451, 2017 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-28097916
9.
Vascular endothelial growth factor receptor-2 (VEGFR-2) inhibitors: development and validation of predictive 3-D QSAR models through extensive ligand- and structure-based approaches.
J Comput Aided Mol Des
; 29(8): 757-76, 2015 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-26194852
10.
Studies on the antiplatelet and antithrombotic profile of anti-inflammatory coumarin derivatives.
J Enzyme Inhib Med Chem
; 30(6): 925-33, 2015 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-25807297
11.
Decreasing acidity in a series of aldose reductase inhibitors: 2-Fluoro-4-(1H-pyrrol-1-yl)phenol as a scaffold for improved membrane permeation.
Bioorg Med Chem
; 22(7): 2194-207, 2014 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24630695
12.
Targeting the anti-apoptotic Bcl-2 family proteins: machine learning virtual screening and biological evaluation of new small molecules.
Theranostics
; 12(5): 2427-2444, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35265218
13.
Essential oils against bacterial isolates from cystic fibrosis patients by means of antimicrobial and unsupervised machine learning approaches.
Sci Rep
; 10(1): 2653, 2020 02 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-32060344
14.
Combined Peptide and Small-Molecule Approach toward Nonacidic THIQ Inhibitors of the KEAP1/NRF2 Interaction.
ACS Med Chem Lett
; 11(5): 740-746, 2020 May 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-32435379
15.
Shmt2: A Stat3 Signaling New Player in Prostate Cancer Energy Metabolism.
Cells
; 8(9)2019 09 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-31500219
16.
Effect of α-Methoxy Substitution on the Anti-HIV Activity of Dihydropyrimidin-4(3 H)-ones.
J Med Chem
; 62(2): 604-621, 2019 01 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-30525601
17.
Development of alkyl glycerone phosphate synthase inhibitors: Structure-activity relationship and effects on ether lipids and epithelial-mesenchymal transition in cancer cells.
Eur J Med Chem
; 163: 722-735, 2019 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30576903
18.
Carotenoid content of Goji berries: CIELAB, HPLC-DAD analyses and quantitative correlation.
Food Chem
; 268: 49-56, 2018 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30064788
19.
Enhancing activity and selectivity in a series of pyrrol-1-yl-1-hydroxypyrazole-based aldose reductase inhibitors: The case of trifluoroacetylation.
Eur J Med Chem
; 130: 328-335, 2017 Apr 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-28259841
20.
Synthesis, biological evaluation and quantitative structure-active relationships of 1,3-thiazolidin-4-one derivatives. A promising chemical scaffold endowed with high antifungal potency and low cytotoxicity.
Eur J Med Chem
; 140: 274-292, 2017 Nov 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-28963991